Varicose Vein Medicine Review

In our modern world, this problem is very acute and widespread among both men and women.We will try to find out the causes, predisposing factors and also talk about treatment methods and drugs used for varicose veins.

Varicose veins are a disease of the veins characterized by their enlargement, change in shape and loss of elasticity.Most often the superficial veins of the lower extremities, the venous plexus of the rectum (hemorrhoids), the veins of the collar and the spermatic cord are affected.

varicose veins in the legs

Predisposing factors

Conditions that contribute to difficulty in the outflow of blood through the venous system, namely:

  • systematic long standing periods associated with professional activities (waiters, pharmacists, hairdressers, salespeople, etc.)
  • compression of the pelvic veins by the pregnant uterus.
  • congestion in the veins of the pelvis, for example, with chronic constipation, sedentary work.
  • congenital weakness of the venous wall and insufficiency of the venous valves.
  • surgery (arteriovenous bypass).
  • hormonal imbalance (menopause, estrogen intake).
  • overweight.

It is important that the true causes of varicose veins are not known.This disease has a progressive character and refers to irreversible changes in the venous vessels.

If we talk about varicose veins of the lower limbs, they are also an aesthetic problem for women.Varicose veins appear visible or bulging under the skin in the form of twisted cords or knots (varicose veins).The skin on them is thin and easily damaged, the reason is a violation of its nutrition.First, dark brown or brown spots appear on the skin, then the veins twist and lift the skin.Over time, if the skin is not properly nourished, trophic ulcers can form.Varicose veins are almost always accompanied by swelling of the extremities, which appear towards the end of the day.This condition leads to rapid fatigue of the legs when walking, a feeling of heaviness and pain in the legs, which intensifies at night.In the absence of proper treatment, the disease progresses and the swelling of the limbs intensifies.Due to the slowing down of blood flow, inflammatory processes can occur in dilated veins, leading to their blockage.

So, the stages of varicose veins:

  • 1 "heavy" leg syndrome.
  • 2 persistent edema develops, accompanied by reduced skin pigmentation and stagnant dermatitis.
  • 3 trophic ulcers appear.

Symptoms of varicose veins of the lower extremities

  • rapid leg fatigue when walking.
  • cramps at night;
  • feeling of heaviness in the legs.
  • leg pain, worse at night.
  • tension in legs;
  • fast heartbeat and shortness of breath.These symptoms occur when the load on the heart muscle increases due to the deposition of blood in the venous bed.

Let's consider when varicose veins are located in other organs:

Varicose veins of the esophagus

Esophageal varices are characterized by tortuosity and saccular growth of blood vessels.The cause of the disease is portal hypertension.

Events:

  • inflammation of the esophagus;
  • burning, belching;
  • anemia;
  • difficulty swallowing.

Complications such as significant bleeding from the veins may develop.The patient presents with vomiting of blood, hypotension, tachycardia and disturbance of consciousness.

Varicose veins of the uterus

Reasons:

  • increased physical activity;
  • chronic constipation;
  • pregnancy;
  • taking hormonal contraceptives.
  • developmental abnormalities;
  • abortions.

Symptoms include lower abdominal pain and menstrual disturbances.A dangerous complication is infertility.

Varicose veins of the lips

It occurs most often in the second month of pregnancy.Predisposing factors are the presence of pelvic vein thrombosis or congenital angiodysplasia.

Events:

  • varicose veins of the vulva.
  • skin scratching and swelling.
  • bursting pain in perineum.

The development of acute thrombophlebitis and rupture of a damaged vessel is possible.

Varicose veins of the pelvis

In the initial stage it manifests itself as an annoying pain in the lower abdomen.There are several variations of the course of this form of the disease:

  • varicose veins of the perineum and vulva.
  • pelvic venous congestion: pain during intercourse, dysmenorrhea, difficulty urinating.

Clinical manifestations of the pathology are observed in 30% of women during pregnancy.This disease is observed exclusively in women.

Varicose veins of the spermatic cord (varicocele)

Due to the varicose veins of the spermatic cord, the venous outflow from the testicles is disturbed.Patients note bothersome pain in the scrotum and erectile dysfunction.On examination in the testicular region, dilated superficial veins and scrotal asymmetry are visible.

Reasons:

  • increased physical activity;
  • congenital connective tissue deficiency.
  • tumors in the retroperitoneum or pelvis.

Possible complications as the disease progresses are spermatogenesis leading to infertility.

Varicose dermatitis

This disease is manifested by thinning and itching of the skin over the affected veins.Dark or light-colored spots and peeling appear in places of inflammation.The main localization of venous dermatitis is the lower leg and the area of the ankle joint.The danger is that patients scratch the itchy areas and the pathological process spreads to healthy tissue.If you do not resort to treatment, the inflammation turns into varicose eczema.

Varicose Eczema

The inflammation is persistent with periods of remission and relapse.Skin lesions are difficult to treat even after phlebectomy.Due to the reduced microcirculation of the skin, the liquid part of the blood passes through the walls of the affected vessels.Swelling and weeping appear in the area above the vein.

Blisters with serous or serous-purulent contents appear on the legs.When scratching, an infection develops in the wounds.Joining, small bubbles form papules.After the opening of the vesicle, crusts appear.The healing area is thinned and covered with scales.During the period of exacerbation, vesicles appear again.The progression of the pathology leads to the formation of trophic ulcers.

Spider veins

Varicose veins - Telangiectasia.It is characterized by damage and dilation of small subcutaneous vessels.They appear on the skin as a purple or red network of blood vessels.In general, it is not a separate disease, but rather acts as a cosmetic defect.

Reasons:

  • venous insufficiency;
  • connective tissue diseases;
  • pathologies of the hepatobiliary system.
  • use of hormonal drugs.
  • diseases of the endocrine system.

Vascular networkit can be found on the legs, face or buttocks area.On the face, the manifestations of the vascular network are called rosacea.

Reasons:

  • violations of the rheological properties of blood.
  • arterial hypertension?
  • diseases of the digestive system;
  • the impact of low temperatures on the skin of the face in a special way.
  • when you drink alcohol.

A common cause of rosacea in women is hormonal changes and is eliminated by laser coagulation.

For varicose veins, preventive measures are of great importance:

  • wearing comfortable shoes and underwear that is not tight.
  • if there is a predisposing factor or disease in the initial stage, then it is necessary to limit or eliminate static loads and prolonged standing.
  • moderate physical activity.
  • intake of vitamins: C, E, PP.
  • balanced diet.

Of course, in the modern world, it is impossible to follow recommendations to limit or eliminate static loads and stay on your feet for long periods of time, so it is necessary to resort to short gymnastics during the day, as well as use massage services.It is also mandatory to wear elastic bandages and compression garments.

Diagnostics

diagnosis of varicose veins

A comprehensive diagnosis is carried out using laboratory methods for the examination of blood and urine (detection of reflux in the saphenous veins, functional tests) and ultrasound examinations: double-sided ultrasound or triple scan.Contrast X-ray venography?magnetic resonance venography?multicoil computed angiography with contrast.

Treatment

treatment of varicose veins

After receiving the diagnostic results, the phlebologist (vascular surgeon) decides on the use of treatment methods - surgery or conservative treatment.

When affecting the vessels of the lower extremities, use:

  • surgery, for example, phlebectomy - removal of a specific vein.
  • sclerotherapy;
  • conservative treatment.

Systemic drug therapy

  1. Antibiotics.(prescribed in the presence of inflammatory processes and trophic ulcers.
  2. Antiseptics?
  3. Phleboprotectors;
  4. Stimulators of tissue regeneration?
  5. Anticoagulants?
  6. Topical steroids (prescribed for peptic ulcers).
  7. Externally - drugs containing heparin.

In this article, we will take a detailed look at vein protectors and external agents used for varicose veins.

Phleboprotectors (Phlebotonics) are a group of drugs used for venous insufficiency.They increase blood circulation, thus normalizing vascular patency, relieving swelling and eliminating the feeling of heaviness.It is important to use them in the initial stages of the disease or to prevent exacerbations.for progressive forms, several courses of treatment are prescribed in different groups.

Review of drugs used for varicose veins.

A natural treatment based on red grape leaf extract.Able to protect the walls of blood vessels and capillaries, improving their elasticity, normalizes vascular permeability.

The product has improved protection of the walls of blood vessels and capillaries.The drug relieves swelling and prevents its recurrence, as it prevents the permeability of water, proteins and plasma through the walls of blood vessels, achieving the restoration of their natural density.

Indicated for:

  • prevention and symptomatic treatment of chronic venous insufficiency.
  • swelling of the lower extremities;
  • with feelings of heaviness and fatigue in the lower limbs.

Contraindicated:

  • people suffering from allergies to one of the components of the composition.

Take 1 capsule after waking up.The doctor may increase the dose to 2 capsules.

Diosmin

The drug is available in tablet form and is sold without a prescription.It refers to phletonic and vasoprotective factors.Diosmin increases the tone of veins, reduces venous stasis, improves permeability and microcirculation of capillaries.It has an anti-inflammatory effect.

Indicated for:

  • varicose veins in the limbs and pelvis.
  • complex treatment of hemorrhoids.
  • signs of venous insufficiency, disorders of lymphatic flow.

Contraindicated:

  • with hypersensitivity to the ingredients.
  • children and adolescents up to 18 years old.

Side effects may include mild digestive upset and headache.Take 1 tablet in the morning.The course of treatment can be quite long, but usually no more than 2 months.

Troxerutinrelieves swelling, normalizes microcirculation and strengthens the walls of blood vessels.It has an anti-inflammatory, antioxidant effect.

Indicated for:

  • chronic venous insufficiency, at any stage of the disease.
  • varicose veins;
  • superficial thrombophlebitis;
  • periphlebitis, phlebitis;
  • varicose dermatitis;
  • postthrombotic syndrome;
  • hemorrhoids;
  • post-traumatic edema and hematomas.
  • hemorrhagic disposition with increased capillary permeability.
  • as a prophylactic after vein surgery.

Troxerutin is used in combination with ascorbic acid to enhance its effects after venous surgery.

Contraindicated:

  • with hypersensitivity;
  • peptic ulcer of the stomach and duodenum.
  • chronic gastritis (in the acute phase).

Not suitable for minors, pregnant women in the first trimester or breastfeeding.The drug Troxerutin should not be used if there are problems with the gastrointestinal tract.In the active stage of fighting the disease, 1 capsule is prescribed with meals three times a day.To maintain the effectiveness of the treatment, the product is applied twice a day.

Rutosidehas an anti-inflammatory effect and fights swelling and heaviness in the legs.The peculiarity of the drug is that it works with blood cells, promoting patency.Thus, the drug for varicose veins helps to fight venous microthrombosis.

Indicated for:

  • chronic venous insufficiency;
  • postvenous syndrome;
  • trophic disorders in varicose veins, trophic ulcers.
  • hemorrhoids (pain, discharge, itching and bleeding).
  • venous insufficiency and hemorrhoids during pregnancy, starting from the second trimester.

Contraindicated:

  • during pregnancy, for a period of 1 to 3 months.

The capsules are used 2-3 times a day, one at a time.

TribenosideIt is available in the form of a cup and a capsule.It has an anti-edematous, anti-inflammatory effect, improves vascular patency.

Indicated for:

  • varicose veins of the lower extremities, including the second and subsequent stages;
  • symptoms of CVI, namely: lymphostasis, blood stagnation, feeling of pain, heaviness, stretching in the calf area, especially at night.
  • phlebitis, periphlebitis, postoperative period.
  • food ulcers;
  • hemorrhoids in chronic and acute phase.

Contraindicated:

  • pregnant women 4-12 months and breastfeeding.

The capsules are taken 2 times a day at regular intervals.

Diosmin with Hesperidin,The medicine is available in the form of film-coated tablets, available without a prescription.The main active ingredients are diosmin with hesperidin.They belong to the group of flenotonic substances and vasoprotective drugs.They help to restore the tone of the venous walls and improve the blood flow in the veins, normalize the function of the valves.

Indications for use:

  • hemorrhoids?
  • varicose veins of the extremities and pelvis.
  • chronic venous insufficiency, including trophic ulcers;

The drug is contraindicated in case of allergic reactions to the components and during breastfeeding.Side effects include only mild indigestion and skin rash.The drug is indicated for complex and natural use.

External treatments for the complex treatment of varicose veins

Ointments and gels are used as external agents.First of all, it is necessary to provide an anti-inflammatory and analgesic effect.For these purposes, non-steroidal anti-inflammatory drugs, as well as general steroid drugs, are used.

Non-steroidal anti-inflammatory drugs (NSAIDs):

  • Ketorolakis?
  • Ketoprofen?
  • Ibuprofen?
  • Nimesulide gel?
  • Diclofenac?

All have a strong anti-inflammatory effect, eliminate pain, discomfort and weight.they are used 1-3 times a day, depending on the stage of the disease, with circular massage actions.Contraindicated in the presence of trophic ulcers and open wounds.

In special cases, steroid drugs are used.If NSAIDs are ineffective.

Prednisolone and its analogues.Inflammation and pain are relieved and local tissue nutrition is improved.It is not used in large quantities because of the possibility of causing generalized side effects.

Swelling Relief:

Corticosteroid-based drugs are used.Restoration of normal blood flow in the legs with varicose veins, stimulating the contraction of the vascular walls:

  • Troxerutin?
  • Diosmin?
  • Rutoside.

Narrow analgesic external drugs are rarely used, due to their limited effect, they do not eliminate the cause, but work with the symptoms:

  • Diclofenac?
  • Ketoprofen.

Heparin-containing medicines contain corticosteroids in addition to heparin.

Compound ointments used for varicose veins of the legs

These drugs have a systemic effect:

  • Sodium heparin (used to relieve swelling, pain, improve local blood flow, prevent the formation of blood clots. It has a rapid therapeutic effect: it is achieved on the second or third day of use).
  • Troxerutin.It relieves pain, swelling, inflammation, normalizes the condition of the veins, ensures adequate venous-lymphatic drainage and prevents the formation of blood clots.
  • Escin.It is prescribed in the early stages of varicose veins, in the later stages it is almost ineffective.It is of plant origin.

Basic principles of treatment with external drugs:

  • do not self-medicate, but seek the help of a phlebologist.
  • strictly follow the instructions for use.
  • analyze the result of treatment effectiveness after 10 days from the date of treatment.

However, even with the combined use of tablets and ointments, gels for external use, you should not count on a quick result, it all depends on the progression of the disease, its stage and the presence of concomitant diseases.

In conclusion, I would like to note that drugs for varicose veins in various locations are not able to completely stop the disease and prevent complications.In the early stage of the disease, flenotonic and vasoprotective drugs help to normalize blood flow in the lower extremities, eliminating symptoms such as swelling, leg fatigue and spider veins, prominent tortuous superficial veins.All these drugs are only part of the treatment, which is directly related to lifestyle and diet.In advanced stages, microsurgical and minimally invasive interventions are indicated while taking drugs that improve treatment results.